“Healthy body, healthy mind” – researchers discover link between exercise training and mental health
In the earlier study, researchers were able to show that trained muscles can help to clean the blood in a way similar to the kidneys and liver.
Through exercise training on the brain, the muscles could convert the stress marker kynurenine into kynurenic acid to speed up metabolism and help people lose weight. High levels of kynurenine - an enzyme produced in certain brain cells - were recorded in people with depression and mental illness by researchers.
For the follow-up study, researchers examined the function of kynurenic acid in more detail and concluded that kynurenic acid could convert white fat into energyburning brown fat.
Dr Ruas said: “We have shown that kynurenic acid prevents weight gain despite excessive energy intake. Our next step is to identify the complex chain of interacting molecules that is affected by diet and training.”
The study was funded by DRWF, the Berth von Kantzow Foundation, the European Research Council, the Erling-Persson Family Foundation, Karolinska Institutet, the Knut and Alice Wallenberg Foundation, the Novo Nordisk Foundation, Skandia, the Stichting af Jochnick Foundation, the Swedish Diabetes Association, the Swedish Society for Medical Research and theSwedish Research Council.
Read the report in Cell Metabolism
Find out more about DRWF-funded research
Find out more about type 2 diabetes
Read the DRWF leaflets A healthy diet and diabetes and Exercise and diabetes here
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